MOTS-c 10mg
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a mitochondrial-derived peptide encoded within the 12S rRNA gene. Research demonstrates AMPK pathway activation, improved glucose metabolism and insulin sensitivity, enhanced exercise capacity, and protection against age-related metabolic dysfunction. It translocates to the nucleus under metabolic stress to regulate gene expression.
Sequence
MRWQEMGYIFYPRKLR
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Volume pricing
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Certificate of Analysis
Independently verified by Janoshik Analytical
Test ID
JAN-MOTSC-2026-001
Purity
98.8%
Method
HPLC-MS
Batch
MOTSC-2026-01A
Test Date
February 1, 2026
Identity
Confirmed
Storage Requirements
Lyophilized
-20°C recommended, protect from light
Reconstituted
2-8°C, use within 14 days
Mitochondrial-derived peptide. Store frozen for long-term stability.
Published Research
2 peer-reviewed studies
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
Lee C, Zeng J, Drew BG, et al. — Cell Metabolism, 2015
Discovery paper demonstrating MOTS-c metabolic effects via AMPK activation.
MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis
Reynolds JC, Lai RW, Woodhead JS, et al. — Nature Communications, 2021
Study linking MOTS-c to exercise-induced metabolic benefits and anti-aging effects.
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Research use only. All products are sold strictly for in-vitro research purposes only. Not for human consumption. Information provided references published research literature. No medical claims are made or implied.